– The difference between primary and secondary hemochromatosis is the cause of the condition.
– Primary hemochromatosis is inherited, meaning it is caused by a genetic mutation that affects how much iron the body absorbs from food whereas secondary hemochromatosis is acquired, meaning it is caused by another medical condition or factor that leads to excess iron in the body.
– Primary hemochromatosis is also known as hereditary hemochromatosis. It is the most common type of hemochromatosis and usually results from a mutation in the HFE gene, which regulates iron absorption. People who inherit two copies of this mutation, one from each parent, have a higher risk of developing hemochromatosis. However, not everyone who has two copies of the mutation will develop symptoms or complications. Other factors, such as age, gender, diet, and alcohol consumption, may also influence the severity of the condition.
– Secondary 0hemochromatosis is also known as acquired hemochromatosis. It occurs when a buildup of iron in the body stems from another medical condition or factor, such as repeated blood transfusions, liver disease, excess iron intake, or erythropoietic hemochromatosis (a rare disorder that causes the red blood cells to release too much iron). Secondary hemochromatosis can affect people of any age or ethnic group and may have different symptoms and treatments than primary hemochromatosis.
– Both types of hemochromatosis can cause serious health problems if left untreated, such as liver damage, heart failure, diabetes, arthritis, and skin discoloration. Therefore, it is important to diagnose and treat hemochromatosis as early as possible to prevent or reduce organ damage and improve quality of life.
